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PCBs are persistent, bioaccumulative, and toxic.













PCBs are found in the blood of anyone tested.



Infants carry higher concetrations of PCBs than their mothers.



These sources show how PCBs


• Bioaccumulate

• Are endocrine disruptors

• Can interfere with immune function, including the response to vaccinations

• May increase insulin resistance and the onset of Type II diabetes

• Cause cancer

• Impair neurodevelopment and induce neurodegeneration — including the brain

• Are in every woman's breast milk








Developing fetuses and infants are the most vulnerable.


Early exposure leads to


Early birth

Low birthweight

Impaired motor development

Delayed learning capability

Sensory integration disorders

Male feminization

Early onset of puberty in females






Exposure has long-term implications


• PCBs (and other POPs) appear to cause more girls to be born than boys.


• PCBs stay in the body long enough to pass from generation to generation.


• Exposure early in life may not show up as disease until decades later.


• The elderly are particularly vulnerable to PCB effects on thyroid function.





Polychlorinated Biphenyls (PCBs) were introduced in the 1900's.

By 1940 their most common toxic effects were understood.

It took more than 30 years to ban them.



PCBs began phasing out in 1973.

By 2000 their use had generally stopped.

Legacy systems may still be using PCBs.



PCB molecules are very stable.

They persist in the environment.

PCBs are in food, air, and water.




Roughly 1.5 million tons of PCBs are thought to have been manufactured.

The true amount may be higher.



PCBs were desirable for their low flammability and electrical insulating properties.



These chlorinated oils were typically used in


Industrial electrical equipment

Flexible plastics

Appliances



They were also used in


Adhesives

Carbonless copy paper

Casting wax

Caulking

Cements

Fabrics

Fluorescent light ballasts

Hydraulic fluids

paints

Pigments

Railroad timber

Thermal insulation (fiberglass, felt, foam, and cork)

Water-proof coatings

Various other applications





Cities and urban areas are generating plumes of PCBs that drift hundreds of miles.


PCBs volatize and spread throughout the environment more easily as temperatures rise.


PCBs can release dioxins during incineration.




Indoor air is a major source of PCB exposure.

Even newer homes and buildings have high levels compared to outside air.



The root sources have not yet been identified.

Building materials are suspected.



Lingering natural gas supply line contamination may be a contributing source.




PCBs are synergistically toxic with many chemicals.


Two examples are PBDEs and mercury.




PCBs have been heavily studied.


More information about PCB toxicity can be found at





New expressions of PCB toxicity continue to be discovered.