
PCBs are persistent, bioaccumulative, and toxic.

PCBs are found in the blood of anyone tested.
Infants carry higher concetrations of PCBs than their mothers.
These sources show how PCBs
• Bioaccumulate
• Are endocrine disruptors
• Can interfere with immune function, including the response to vaccinations
• May increase insulin resistance and the onset of Type II diabetes
• Cause cancer
• Impair neurodevelopment and induce neurodegeneration — including the brain
• Are in every woman's breast milk
• Are endocrine disruptors
• Can interfere with immune function, including the response to vaccinations
• May increase insulin resistance and the onset of Type II diabetes
• Cause cancer
• Impair neurodevelopment and induce neurodegeneration — including the brain
• Are in every woman's breast milk
Developing fetuses and infants are the most vulnerable.
Early exposure leads to
Early birth
Low birthweight
Impaired motor development
Delayed learning capability
Sensory integration disorders
Male feminization
Early onset of puberty in females
Low birthweight
Impaired motor development
Delayed learning capability
Sensory integration disorders
Male feminization
Early onset of puberty in females
Exposure has long-term implications
• PCBs (and other POPs)
appear to cause more girls to be born than boys.
• PCBs stay in the body long enough to pass from generation to generation.
• Exposure early in life may not show up as disease until decades later.
• The elderly are particularly vulnerable to PCB effects on thyroid function.
• PCBs stay in the body long enough to pass from generation to generation.
• Exposure early in life may not show up as disease until decades later.
• The elderly are particularly vulnerable to PCB effects on thyroid function.

Polychlorinated Biphenyls (PCBs) were introduced in the 1900's.
By 1940 their most common toxic effects were understood.
It took more than 30 years to ban them.
PCBs began phasing out in 1973.
By 2000 their use had generally stopped.
Legacy systems may still be using PCBs.
PCB molecules are very stable.
They persist in the environment.
PCBs are in food, air, and water.
Roughly 1.5 million tons of PCBs are thought to have been manufactured.
The true amount may be higher.
PCBs were desirable for their low flammability and electrical insulating properties.
These chlorinated oils were typically used in
Industrial electrical equipment
Flexible plastics
Appliances
Flexible plastics
Appliances

They were also used in
Adhesives
Carbonless copy paper
Casting wax
Caulking
Cements
Fabrics
Fluorescent light ballasts
Hydraulic fluids
paints
Pigments
Railroad timber
Thermal insulation (fiberglass, felt, foam, and cork)
Water-proof coatings
Various other applications
Carbonless copy paper
Casting wax
Caulking
Cements
Fabrics
Fluorescent light ballasts
Hydraulic fluids
paints
Pigments
Railroad timber
Thermal insulation (fiberglass, felt, foam, and cork)
Water-proof coatings
Various other applications
Cities and urban areas are generating plumes of PCBs that drift hundreds of miles.
PCBs volatize and spread throughout the environment more easily as temperatures rise.
PCBs can release dioxins during incineration.
Indoor air is a major source of PCB exposure.
Even newer homes and buildings have high levels compared to outside air.
The root sources have not yet been identified.
Building materials are suspected.
Lingering natural gas supply line contamination may be a contributing source.
PCBs are synergistically toxic with many chemicals.
Two examples are PBDEs and mercury.
PCBs have been heavily studied.
More information about PCB toxicity can be found at
New expressions of PCB toxicity continue to be discovered.